Description

7-Boc-7-Azaspiro[3.5]Nonane-2-Methanol is a high-purity, protected amino alcohol building block of significant interest in advanced organic synthesis. This compound is valued for its rigid spirocyclic scaffold and functional handles, which are crucial for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to introduce conformational constraint and modulate physicochemical properties.
• Peptidomimetics: Serves as a constrained scaffold for designing and synthesizing peptide mimics with enhanced metabolic stability and bioavailability.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Agrochemical Research: Utilized as a building block in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Acts as a core structure for developing molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	7-Boc-7-Azaspiro[3.5]Nonane-2-Methanol
CAS No.	1356476-27-1
Molecular Formula	C14H25NO3
Molecular Weight	255.35 g/mol
Synonyms	2-(Hydroxymethyl)-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester; tert-Butyl 2-(hydroxymethyl)-7-azaspiro[3.5]nonane-7-carboxylate; 7-Boc-7-azaspiro[3.5]nonan-2-ylmethanol; 7-(tert-Butoxycarbonyl)-7-azaspiro[3.5]nonane-2-methanol; Boc-7-Azaspiro[3.5]Nonane-2-Methanol; N-Boc-7-Azaspiro[3.5]nonane-2-methanol; 7-Azaspiro[3.5]nonane-2-methanol, 7-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our 7-Boc-7-Azaspiro[3.5]Nonane-2-Methanol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.