Description

Benzaldehyde, 2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, multi-functional chemical intermediate that combines a benzaldehyde core with a boronic ester pinacol protecting group. This compound matters for its critical role in modern synthetic chemistry, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially those containing biphenyl or heteroaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science: Serves as a precursor for organic electronic materials, such as OLEDs and semiconductors.
• Cross-Coupling Reactions: An essential reagent in palladium-catalyzed Suzuki-Miyaura couplings for C-C bond formation.
• Chemical Research: Employed in academic and industrial R&D for methodology development and library synthesis.
• Ligand and Catalyst Development: Used to create novel bidentate or tridentate ligands for catalytic systems.

Basic Information

Product Name	Benzaldehyde, 2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1356401-39-2
Molecular Formula	C₁₃H₁₆BClO₃
Molecular Weight	266.53 g/mol
Synonyms	2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; (2-Chloro-3-formylphenyl)boronic acid pinacol ester; 2-Chloro-3-(pinacolatoboryl)benzaldehyde; 3-Formyl-2-chlorophenylboronic acid pinacol ester; 2-Chloro-3-boronobenzaldehyde pinacol ester; 2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenecarboxaldehyde; B-(2-Chloro-3-formylphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Benzaldehyde, 2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for sensitive applications like pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.