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Imidazo[1,2-A]Pyridine, 3-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- CAS NO 1356400-75-3


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CAS No.:1356400-75-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Imidazo[1,2-A]Pyridine, 3-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, functionalized heterocyclic boronic ester derivative. This compound matters as a critical pharmaceutical intermediate and versatile Suzuki-Miyaura cross-coupling building block, enabling the synthesis of complex molecules. It is primarily needed by R&D chemists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active compounds.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing drug candidates, particularly in kinase inhibitor and antiviral research.
  • Suzuki-Miyaura Cross-Coupling Reactions: Enables the formation of carbon-carbon bonds to attach complex aryl and heteroaryl groups.
  • Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
  • Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or emissive layer materials.
  • Ligand Synthesis for Catalysis: Used to create novel nitrogen-containing ligands for transition metal catalysts.
  • Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways.
  • Polymer & Material Science: A monomer or functionalization agent for creating specialty polymers with tailored properties.
  • Academic & Contract Research: Essential reagent for methodological development and discovery chemistry in research institutions and CROs.

Basic Information

Item Details
Product Name Imidazo[1,2-A]Pyridine, 3-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No. 1356400-75-3
Molecular Formula C14H19BN2O2
Molecular Weight 258.13 g/mol
Synonyms 3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methylimidazo[1,2-a]pyridine; 3-Methylimidazo[1,2-a]pyridine-6-boronic acid pinacol ester; (3-Methylimidazo[1,2-a]pyridin-6-yl)boronic acid pinacol ester; CAS 1356400-75-3
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Quality Control

Our Imidazo[1,2-A]Pyridine boronic ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and potential decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Retention time corresponds to reference standard
Identification (NMR) Spectrum consistent with structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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