Description

Methyl 1-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Piperidine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a valuable boronic ester pinacol group. This compound is essential for modern synthetic chemistry, enabling efficient cross-coupling reactions like the Suzuki-Miyaura reaction to construct complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Suzuki-Miyaura Cross-Coupling: Serves as a crucial boron-containing coupling partner for forming carbon-carbon bonds between aromatic and heteroaromatic systems.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the piperidine and pyridine motifs are common structural features.
• Material Science Precursor: Potential intermediate for creating organic electronic materials and ligands for catalytic systems.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	Methyl 1-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Piperidine-3-Carboxylate
CAS No.	1356363-82-0
Molecular Formula	C20H31BN2O4
Molecular Weight	374.28 g/mol
Synonyms	Methyl 1-[4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperidine-3-carboxylate; 3-Piperidinecarboxylic acid, 1-[4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-, methyl ester; Methyl 1-(4-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperidine-3-carboxylate; 1356363-82-0; Boronic acid, B-[6-(3-methoxycarbonyl-1-piperidinyl)-4-methyl-3-pyridinyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our Methyl 1-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Piperidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.