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2-(1-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Piperidin-3-Yl)Ethanol CAS NO 1356363-80-8


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CAS No.:1356363-80-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(1-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Piperidin-3-Yl)Ethanol is a sophisticated boronic ester derivative, a key building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially in Suzuki-Miyaura cross-coupling reactions for creating biaryl and heterobiaryl structures.
  • Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the boronic ester moiety facilitates the introduction of complex pyridine-piperidine scaffolds.
  • Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysis, and other functional organic compounds.
  • Chemical Biology Probes: Employed in the development of molecular probes and tools for studying biological processes due to its reactive handle for bioconjugation.
  • Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name 2-(1-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Piperidin-3-Yl)Ethanol
CAS No. 1356363-80-8
Molecular Formula C20H31BN2O3
Molecular Weight 358.29 g/mol
Synonyms 2-[1-[4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperidin-3-yl]ethanol; 2-(1-(4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperidin-3-yl)ethan-1-ol; 2-(3-(2-Hydroxyethyl)piperidin-1-yl)-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol ester of (6-(3-(2-Hydroxyethyl)piperidin-1-yl)-5-methylpyridin-3-yl)boronic acid
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Quality Control

Our 2-(1-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Piperidin-3-Yl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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