Description

4-Methyl-2-(4-Methyl-1H-Imidazol-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional heterocyclic compound featuring both an imidazole ring and a pinacol boronate ester group. This unique structure makes it a critical building block in modern synthetic chemistry, particularly for cross-coupling reactions like the Suzuki-Miyaura reaction. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require precise, high-purity intermediates for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its boronate functionality for structural diversification.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Synthesis: An essential reagent in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds under mild conditions.
• Ligand Synthesis: Used to prepare complex ligands for catalysis and metal-organic frameworks (MOFs).
• Bioconjugation: Potential use in bioconjugation chemistry for labeling biomolecules due to its reactive boronate group.

Basic Information

Product Name	4-Methyl-2-(4-Methyl-1H-Imidazol-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1356363-79-5
Molecular Formula	C16H22BN3O2
Molecular Weight	299.18 g/mol
Synonyms	2-(4-Methyl-1H-imidazol-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methylpyridine; 4-Methyl-2-(4-methylimidazol-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(4-methyl-1H-imidazol-1-yl)-4-methylpyridine; 1356363-79-5; Boronic acid, B-[2-(4-methyl-1H-imidazol-1-yl)-4-methyl-5-pyridinyl]-, pinacol ester; Pyridine, 4-methyl-2-(4-methyl-1H-imidazol-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
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Quality Control

Our 4-Methyl-2-(4-Methyl-1H-Imidazol-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.