Description

2-Hydrazinyl-4-Methyl-5-(4,4,5-Trimethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional heterocyclic building block that integrates a pyridine core with both hydrazinyl and boronic ester functional groups. This unique structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, particularly in medicinal chemistry for creating targeted covalent inhibitors and in materials science for developing functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors and other targeted therapies utilizing boronic acid chemistry.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides with specific modes of action.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers, sensors, and organic electronic materials.
• Cross-Coupling Reactions: The boronic ester moiety makes it a valuable substrate in Suzuki-Miyaura cross-coupling reactions for constructing complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-ligand interactions.
• Ligand Synthesis: Acts as a precursor for creating novel chelating ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Hydrazinyl-4-Methyl-5-(4,4,5-Trimethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1356363-77-3
Molecular Formula	C14H22BN3O2
Molecular Weight	275.16 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-hydrazinyl-4-methylpyridine; 2-Hydrazino-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-hydrazine; 2-Hydrazinyl-4-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; PINAP Hydrazine Derivative; Pyridine Boronic Ester Hydrazine
EINECS	Contact for details

Quality Control

Our 2-Hydrazinyl-4-Methyl-5-(4,4,5-Trimethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC, NMR, and MS, are validated to provide reliable data for critical R&D work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.