Description

n-(2-Methoxyethyl)-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-value, functionalized pyridine boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery, ligand synthesis, and the development of functional organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Material Science: Precursor for creating organic electronic materials, such as ligands for OLEDs (Organic Light-Emitting Diodes) and conductive polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for target identification and protein labeling.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel chiral or bidentate ligands used in asymmetric catalysis.
• Academic & Contract Research: A versatile reagent for methodological development and complex molecule synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	n-(2-Methoxyethyl)-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1356363-65-9
Molecular Formula	C15H25BN2O3
Molecular Weight	292.19 g/mol
Synonyms	2-Amino-N-(2-methoxyethyl)-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(2-methoxyethyl)pyridin-2-amine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methyl-N-(2-methoxyethyl)pyridin-2-amine; Pinacol ester of [5-Amino-6-((2-methoxyethyl)amino)-3-methylpyridin-2-yl]boronic acid; Boronic acid, B-[5-amino-6-[(2-methoxyethyl)amino]-3-methyl-2-pyridinyl]-, 1,1-dimethylethyl ester; CAS 1356363-65-9
EINECS	Contact for details

Quality Control

Our production of n-(2-Methoxyethyl)-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with customer-specific requirements and general industry standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.