Description

2-sec-Butoxy-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, advanced pharmaceutical intermediate and building block in organic synthesis. This compound matters for its role as a key precursor in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex pyridine and biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Serves as a monomer or precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Cross-Coupling Reactions: An essential boron reagent for palladium-catalyzed Suzuki-Miyaura couplings, facilitating carbon-carbon bond formation under mild conditions.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological systems and drug-target interactions.

Basic Information

Item	Details
Product Name	2-sec-Butoxy-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1356363-46-6
Molecular Formula	C16H26BNO3
Molecular Weight	291.20 g/mol
Synonyms	2-(sec-Butoxy)-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Methyl-2-(sec-butoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(sec-butoxy)-3-methylpyridine; 2-(1-Methylpropoxy)-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pyridineboronic acid, 2-(sec-butoxy)-3-methyl-, pinacol ester; Boronic ester intermediate 1356363-46-6; Suzuki coupling reagent
EINECS	Contact for details

Quality Control

Our 2-sec-Butoxy-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency suitable for sensitive cross-coupling applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, as the boronic ester moiety can be sensitive to moisture and prolonged exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.