Description

2-Bromo-1,3-Dimethyl-5-(Trifluoromethyl)Benzene is a high-value halogenated aromatic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications in cross-coupling reactions and as a key intermediate in the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity.
• Material Science: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research: Employed in academic and industrial laboratories for method development and exploring new synthetic pathways in organic chemistry.
• Ligand and Catalyst Development: Used to synthesize novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2-Bromo-1,3-Dimethyl-5-(Trifluoromethyl)Benzene
CAS No.	1356114-12-9
Molecular Formula	C9H8BrF3
Molecular Weight	253.06 g/mol
Synonyms	1-Bromo-3,5-dimethyl-2-(trifluoromethyl)benzene; 3,5-Dimethyl-2-(trifluoromethyl)bromobenzene; 2-Bromo-α,α,α-trifluoro-3,5-xylene; 2-Bromo-3,5-dimethylbenzotrifluoride; 2-Bromo-1,3-dimethyl-5-(trifluoromethyl)benzene; Bromo-dimethyl-trifluoromethylbenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-1,3-Dimethyl-5-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support compliance with relevant regulatory frameworks for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.