Description

(2-(Benzyloxy)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)(Pyrrolidin-1-Yl)Methanone is a high-purity, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound is a critical building block in modern medicinal chemistry, enabling efficient cross-coupling reactions for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly in oncology and CNS therapeutic areas.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl scaffolds in drug discovery pipelines.
• Pharmaceutical Intermediate: Serves as a versatile building block in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop novel therapeutic agents.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for target identification and validation in biological systems.
• Process Chemistry Development: Supports scale-up and route scouting for efficient manufacturing of complex organic molecules.
• Material Science Research: Potential precursor for organic electronic materials and ligands in catalytic systems.

Basic Information

Product Name	(2-(Benzyloxy)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)(Pyrrolidin-1-Yl)Methanone
CAS No.	1356111-54-0
Molecular Formula	C24H30BNO4
Molecular Weight	407.31 g/mol
Synonyms	1-(2-(Benzyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrrolidin-1-one; 2-(Benzyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-pyrrolidin-1-ylbenzamide; (2-Benzyloxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(pyrrolidin-1-yl)methanone; B-(2-Benzyloxy-5-(1-pyrrolidinylcarbonyl)phenyl)boronic acid pinacol ester; 1356111-54-0; Boronic acid, B-[2-(phenylmethoxy)-5-(1-pyrrolidinylcarbonyl)phenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our (2-(Benzyloxy)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)(Pyrrolidin-1-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain stability and purity. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.