Description

1-Bromo-2-Fluoro-3-(Phenylaminomethyl)Benzene is a high-purity, multi-functional aromatic building block featuring bromine, fluorine, and an aniline-derived substituent. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of key pharmacophores and structural motifs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the halogen and aniline motifs for bioactivity.
• Ligand and Catalyst Development: Acts as a starting material for constructing complex ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or fluorophore cores for OLEDs.
• Custom Chemical Synthesis: Provides a versatile scaffold for contract research organizations (CROs) and CDMOs to build bespoke compounds for client projects.
• Life Science Reagents: Utilized in the preparation of biochemical probes and tool compounds for proteomics and diagnostic assay development.

Basic Information

Product Name	1-Bromo-2-Fluoro-3-(Phenylaminomethyl)Benzene
CAS No.	1355247-92-5
Molecular Formula	C13H11BrFN
Molecular Weight	280.14 g/mol
Synonyms	3-(Benzylamino)-2-fluorobromobenzene; 2-Fluoro-3-(phenylaminomethyl)bromobenzene; 1-Bromo-2-fluoro-3-[(phenylamino)methyl]benzene; N-[(3-Bromo-2-fluorophenyl)methyl]aniline; Benzenemethanamine, N-(3-bromo-2-fluorophenyl)-; (3-Bromo-2-fluorobenzyl)(phenyl)amine
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Fluoro-3-(Phenylaminomethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.