Description

1-Chloro-3-Fluoro-5-(3-Nitrophenyl)Benzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. Its unique structure, featuring chloro, fluoro, and nitro substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key precursor in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of its halogenated nitroaromatic structure.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce functionalized aryl groups into target molecules.
• Dye and Pigment Intermediate: Acts as a precursor in the manufacture of complex, high-performance dyes and organic pigments.

Basic Information

Product Name	1-Chloro-3-Fluoro-5-(3-Nitrophenyl)Benzene
CAS No.	1355247-83-4
Molecular Formula	C12H7ClFNO2
Molecular Weight	251.64 g/mol
Synonyms	3'-Nitro-5-chloro-3-fluorobiphenyl; 1-Chloro-3-fluoro-5-(3-nitrophenyl)benzene; 3-Chloro-5-fluoro-3'-nitro-1,1'-biphenyl; 5-Chloro-3'-fluoro-3-nitro-1,1'-biphenyl; (3-Nitrophenyl)-3-chloro-5-fluorobenzene; 3-Chloro-5-fluoro-3'-nitrobiphenyl
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Fluoro-5-(3-Nitrophenyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.