Description

6-Chloro-2-Morpholinonicotinaldehyde is a high-value, functionalized nicotinaldehyde derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a chloro-substituent and a morpholino group, makes it an indispensable intermediate for constructing complex molecules with specific pharmacological or material properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology Probe Synthesis: Serves as a versatile handle for creating molecular probes and labeled compounds used in biochemical and cellular studies.
• Material Science: Building block for synthesizing specialized ligands, catalysts, and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns.

Basic Information

Product Name	6-Chloro-2-Morpholinonicotinaldehyde
CAS No.	1355247-67-4
Molecular Formula	C10H11ClN2O2
Molecular Weight	226.66 g/mol
Synonyms	6-Chloro-2-morpholin-4-ylpyridine-3-carbaldehyde; 3-Pyridinecarboxaldehyde, 6-chloro-2-(4-morpholinyl)-; 6-Chloro-2-(morpholin-4-yl)nicotinaldehyde; 2-Morpholino-6-chloronicotinaldehyde; 6-Chloro-2-(4-morpholinyl)-3-pyridinecarboxaldehyde; 6-Chloro-2-morpholinopyridine-3-carboxaldehyde; 1355247-67-4 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-2-Morpholinonicotinaldehyde is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA) that include results from HPLC, NMR, and MS. Our quality commitment aligns with the standards expected for non-GMP pharmaceutical intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.