Description

1-Bromo-2-Fluoro-3-(Butylaminomethyl)Benzene is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique halogen and amine substitution pattern, which enables precise molecular modifications in complex organic syntheses. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated benzene core.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and functional polymers.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.
• Academic Research: Used in university and institutional labs for methodological studies in cross-coupling and amination reactions.

Basic Information

Product Name	1-Bromo-2-Fluoro-3-(Butylaminomethyl)Benzene
CAS No.	1355247-01-6
Molecular Formula	C11H15BrFN
Molecular Weight	260.15 g/mol
Synonyms	3-(Butylaminomethyl)-1-bromo-2-fluorobenzene; 2-Fluoro-3-(butylaminomethyl)bromobenzene; 1-Bromo-2-fluoro-3-[(butylamino)methyl]benzene; Benzenamine, N-butyl-5-bromo-6-fluoro-; (3-Bromo-2-fluorophenyl)methylbutylamine; Butyl-[(3-bromo-2-fluorophenyl)methyl]amine
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-2-Fluoro-3-(Butylaminomethyl)Benzene is produced and tested under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, GC, and NMR is provided with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.