Description

2-(Benzyloxy)-5-Bromobenzaldehyde, Dimethyl Acetal is a high-purity, advanced pharmaceutical intermediate characterized by its protected aldehyde functionality. This compound is critical for enabling complex synthetic routes in medicinal chemistry, offering enhanced stability and selectivity during multi-step reactions. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the bromo and benzyloxy substituents for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic semiconductors and photoactive materials due to its conjugated aromatic system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production and scale-up projects.

Basic Information

Product Name	2-(Benzyloxy)-5-Bromobenzaldehyde, Dimethyl Acetal
CAS No.	1355247-00-5
Molecular Formula	C₁₆H₁₇BrO₃
Molecular Weight	337.21 g/mol
Synonyms	5-Bromo-2-(benzyloxy)benzaldehyde dimethyl acetal; Benzaldehyde, 5-bromo-2-(phenylmethoxy)-, dimethyl acetal; 1-(5-Bromo-2-(benzyloxy)phenyl)-2,2-dimethoxyethan-1-one (tautomeric form); 2-Benzyloxy-5-bromobenzaldehyde dimethyl acetal; Dimethyl [5-bromo-2-(phenylmethoxy)phenyl]methanediol Formal
EINECS	Contact for details

Quality Control

Every batch of 2-(Benzyloxy)-5-Bromobenzaldehyde, Dimethyl Acetal is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles via validated methods such as HPLC, GC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.