Description

6-(4-Isopropylpiperazin-1-Yl)Nicotinaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining a nicotinaldehyde core with an isopropylpiperazine moiety. This compound is of significant value in modern organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for projects targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas requiring sophisticated nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates and novel chemical entities for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a versatile building block for constructing libraries of compounds in structure-activity relationship (SAR) studies.
• Ligand and Receptor Probe Development: Employed in the design and synthesis of ligands for neurological and GPCR targets due to its piperazine pharmacophore.
• Agrochemical Research: Serves as an intermediate in the development of new crop protection agents and pesticides.
• Chemical Biology: Utilized in the synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of specific, high-value compounds under cGMP or research-grade conditions.

Basic Information

Product Name	6-(4-Isopropylpiperazin-1-Yl)Nicotinaldehyde
CAS No.	1355238-58-2
Molecular Formula	C13H19N3O
Molecular Weight	233.31 g/mol
Synonyms	6-(4-Isopropyl-1-piperazinyl)-3-pyridinecarboxaldehyde; 6-(4-Isopropylpiperazin-1-yl)pyridine-3-carbaldehyde; 3-Pyridinecarboxaldehyde, 6-(4-(1-methylethyl)-1-piperazinyl)-; 6-(4-Isopropylpiperazin-1-yl)nicotinaldehyde; 6-(4-Isopropylpiperazin-1-yl)nicotinaldehyde CAS 1355238-58-2; 6-(4-Propan-2-ylpiperazin-1-yl)pyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 6-(4-Isopropylpiperazin-1-Yl)Nicotinaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports research and development requiring high-purity intermediates for reliable and reproducible results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.