Description

5-Methyl-6-(Pyrrolidin-1-Yl)Nicotinaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique nicotinaldehyde core substituted with a pyrrolidine ring. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Used in the construction of complex heterocyclic compounds due to its reactive aldehyde and substituted pyridine functionalities.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	5-Methyl-6-(Pyrrolidin-1-Yl)Nicotinaldehyde
CAS No.	1355206-00-6
Molecular Formula	C12H16N2O
Molecular Weight	204.27 g/mol
Synonyms	6-(Pyrrolidin-1-yl)-5-methylnicotinaldehyde; 5-Methyl-6-(1-pyrrolidinyl)-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 5-methyl-6-(1-pyrrolidinyl)-; 5-Methyl-6-pyrrolidin-1-ylpyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Methyl-6-(Pyrrolidin-1-Yl)Nicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is easily oxidized and light-sensitive. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.