Description

1,3,2-Dioxaborolane, 2-[(1E)-2-(2-Chlorophenyl)Ethenyl]-4,4,5,5-Tetramethyl- is a high-value, organoboron building block featuring a reactive vinylboronate ester group. This compound is critical for enabling advanced cross-coupling reactions, particularly in the synthesis of complex pharmaceutical intermediates and functional materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between the vinyl group and aryl/heteroaryl halides, essential for creating complex organic molecules.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), especially those containing styryl or biaryl motifs.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science & OLED Development: Serves as a precursor for constructing organic semiconductors, light-emitting materials, and other functional polymers.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules due to the bioorthogonal reactivity of the boronate ester.
• Academic & Industrial R&D: A versatile tool for methodological development in synthetic organic chemistry and catalysis studies.

Basic Information

Item	Detail
Product Name	1,3,2-Dioxaborolane, 2-[(1E)-2-(2-Chlorophenyl)Ethenyl]-4,4,5,5-Tetramethyl-
CAS No.	1355094-04-0
Molecular Formula	C14H18BClO2
Molecular Weight	264.55 g/mol
Synonyms	(E)-2-(2-Chlorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-[(1E)-2-(2-Chlorophenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-2-(2-Chlorovinylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; trans-2-(2-Chlorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(2-Chloro-β-styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (E)-2-(2-chlorostyryl)boronate; (E)-2-(2-Chlorostyryl)pinacolboronate
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 2-[(1E)-2-(2-Chlorophenyl)Ethenyl]-4,4,5,5-Tetramethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.