Description

(6-Bromo-5-Chloropyridin-3-Yl)Boronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative, essential for modern cross-coupling reactions. Its core value lies in enabling the precise construction of complex heterocyclic scaffolds, which are critical in advanced material and pharmaceutical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for introducing the 6-bromo-5-chloropyridin-3-yl moiety into complex molecules, enabling carbon-carbon bond formation under mild conditions.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Chemical Biology & Probe Development: Utilized to create molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(6-Bromo-5-Chloropyridin-3-Yl)Boronic Acid Pinacol Ester
CAS No.	1355070-59-5
Molecular Formula	C13H16BBrClNO2
Molecular Weight	348.44 g/mol
Synonyms	5-Chloro-6-bromopyridin-3-ylboronic acid pinacol ester; (6-Bromo-5-chloro-3-pyridinyl)boronic acid pinacol ester; 3-Bromo-2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Chloro-3-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; (6-Bromo-5-chloro-3-pyridyl)boronic acid pinacol ester; Boronic acid, B-(6-bromo-5-chloro-3-pyridinyl)-, 1,1-dimethylethyl ester; Pinacol (6-bromo-5-chloropyridin-3-yl)boronate
EINECS	Contact for details

Quality Control

Our (6-Bromo-5-Chloropyridin-3-Yl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring consistency and reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.