Description

Benzyl n-{4-Aminobicyclo[2.1.1]Hexan-1-Yl}Carbamate Hydrochloride is a high-purity, protected amine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Peptidomimetics & PROTACs: Used in the synthesis of peptide mimics and Proteolysis-Targeting Chimeras (PROTACs) due to its rigid bicyclic scaffold and protected amine functionality.
• Agrochemical Research: Acts as a building block for creating new crop protection agents and herbicides with potentially novel modes of action.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science: Utilized in the development of specialty polymers and advanced functional materials requiring specific amine-based monomers.
• Chemical Biology Probes: Incorporated into molecular probes and tags for studying biological processes and target engagement.

Basic Information

Item	Detail
Product Name	Benzyl n-{4-Aminobicyclo[2.1.1]Hexan-1-Yl}Carbamate Hydrochloride
CAS No.	1354951-84-0
Molecular Formula	C15H20N2O2 • HCl
Molecular Weight	296.79 g/mol (Free base: 260.33 g/mol)
Synonyms	Benzyl (4-Aminobicyclo[2.1.1]hexan-1-yl)carbamate Hydrochloride; 1-(((Benzyloxy)carbonyl)amino)bicyclo[2.1.1]hexan-4-amine Hydrochloride; 4-Aminobicyclo[2.1.1]hexane-1-carboxylic acid benzyl ester hydrochloride; Bicyclo[2.1.1]hexan-4-amine, 1-[[(phenylmethoxy)carbonyl]amino]-, hydrochloride (1:1); Cbz-Protected 4-Aminobicyclo[2.1.1]hexylamine HCl; N-Cbz-4-Aminobicyclo[2.1.1]hexylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our Benzyl n-{4-Aminobicyclo[2.1.1]Hexan-1-Yl}Carbamate Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.