Description

4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-n-m-Tolylpyridin-2-Amine is a high-value, organoboron building block essential for modern synthetic chemistry, specifically designed for Suzuki-Miyaura cross-coupling reactions. Its core value lies in enabling the efficient and selective formation of carbon-carbon bonds, a fundamental step in constructing complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery and development programs.
• Agrochemical Synthesis: Used to construct novel herbicide, fungicide, and insecticide candidates with improved efficacy and selectivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands and metal-organic complexes for catalytic applications.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying biological pathways and target engagement.
• Academic & Contract Research: A vital reagent for methodology development and complex molecule synthesis in academic and CRO laboratories.

Basic Information

Product Name	4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-n-m-Tolylpyridin-2-Amine
CAS No.	1354911-21-9
Molecular Formula	C19H25BN2O2
Molecular Weight	324.23 g/mol
Synonyms	2-Amino-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(3-methylphenyl)pyridine; N-(3-Methylphenyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methylpyridin-2-amine; 4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(m-tolyl)pyridin-2-amine; m-Tolyl Boronic Acid Pinacol Ester Pyridine Derivative; Suzuki Coupling Boronate Ester Intermediate; Bpin-Pyridine-Toluidine Derivative
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-n-m-Tolylpyridin-2-Amine adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. All material is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.