Description

n-(3-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Ylamino)Propyl)Acetamide is a high-value pharmaceutical intermediate and chemical building block featuring a protected boronic ester group. This compound is critical for enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental to modern medicinal chemistry and materials science. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds for constructing biaryl and heterobiaryl structures essential in drug discovery.
• Agrochemical Research: Used in the development of new pesticides and herbicides that require specific boronate-containing scaffolds.
• Material Science: Serves as a precursor for organic semiconductors, OLED materials, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the design of activity-based probes and bioconjugation reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	n-(3-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Ylamino)Propyl)Acetamide
CAS No.	1354911-10-6
Molecular Formula	C19H32BN3O3
Molecular Weight	361.29 g/mol
Synonyms	N-[3-[[4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]amino]propyl]acetamide; 2-Pyridinamine, N-[3-(acetylamino)propyl]-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Acetamide, N-[3-[[4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]amino]propyl]-; 1354911-10-6; 4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(3-(acetamido)propyl)pyridin-2-amine; Boronic ester pyridine derivative
EINECS	Contact for details

Quality Control

Our n-(3-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Ylamino)Propyl)Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Production can be aligned with research-grade or cGMP standards based on customer requirements to support preclinical and clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.