Description

4-Methyl-n-(3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Benzenesulfonamide is a high-value, organoboron-containing intermediate critical for modern synthetic chemistry, particularly in cross-coupling reactions. This compound is engineered to provide a protected boronic ester functionality, offering superior stability and reactivity for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific aryl-aryl bond formations.
• Material Science Research: Serves as a precursor in the development of organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for target identification and biomarker studies.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries in medicinal chemistry programs through efficient coupling methodologies.
• Ligand and Catalyst Development: Acts as a starting material for creating novel ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Item	Detail
Product Name	4-Methyl-n-(3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Benzenesulfonamide
CAS No.	1354910-95-4
Molecular Formula	C20H27BN2O4S
Molecular Weight	402.32 g/mol
Synonyms	4-Methyl-N-[3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]benzenesulfonamide; 2-Pyridinesulfonamide, N-(4-methylphenyl)-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1354910-95-4; 4-Methyl-N-(3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)benzenesulfonamide; Benzenesulfonamide, 4-methyl-N-[3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-
EINECS	Contact for details

Quality Control

Our 4-Methyl-n-(3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Benzenesulfonamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect the moisture-sensitive boronic ester functionality from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.