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2-(2-Methoxyethoxy)-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine CAS NO 1354712-71-2


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CAS No.:1354712-71-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(2-Methoxyethoxy)-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, functionalized pyridine boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex heterocyclic structures.
  • Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other functional organic electronic components.
  • Ligand & Catalyst Design: Employed in the synthesis of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
  • Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Utilized as a linker or functional handle in the design of bifunctional molecules for targeted protein degradation.
  • Academic & Contract Research: A vital reagent for university laboratories and CROs (Contract Research Organizations) engaged in methodological development and complex molecule synthesis.

Basic Information

Item Details
Product Name 2-(2-Methoxyethoxy)-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No. 1354712-71-2
Molecular Formula C15H24BNO4
Molecular Weight 293.17 g/mol
Synonyms 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(2-methoxyethoxy)pyridine; 2-(2-Methoxyethoxy)-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(2-methoxyethoxy)-3-methylpyridine; Pinacol ester of [2-(2-Methoxyethoxy)-3-methyl-5-pyridyl]boronic acid; Pyridine-5-boronic acid, 2-(2-methoxyethoxy)-3-methyl-, pinacol ester
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Quality Control

Our 2-(2-Methoxyethoxy)-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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