Description

(2-Aminomethyl-Piperidin-1-Yl)-Benzo[1,3]Dioxol-5-Yl-Methanone Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular targeting. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and other therapeutic targets.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a critical starting material or intermediate in the scale-up and optimization of API manufacturing processes.
• Custom Synthesis: A valuable scaffold for contract research and manufacturing organizations (CROs/CMOs) producing bespoke molecules for clients.
• Chemical Biology: Can be utilized in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Product Name	(2-Aminomethyl-Piperidin-1-Yl)-Benzo[1,3]Dioxol-5-Yl-Methanone Hydrochloride
CAS No.	1353985-61-1
Molecular Formula	C15H21ClN2O3
Molecular Weight	312.79 g/mol
Synonyms	1-(1,3-Benzodioxol-5-ylcarbonyl)-2-(aminomethyl)piperidine hydrochloride; 2-(Aminomethyl)-1-(1,3-benzodioxole-5-carbonyl)piperidine hydrochloride; (2-Aminomethyl-1-piperidyl)(1,3-benzodioxol-5-yl)methanone hydrochloride; Piperidine, 2-(aminomethyl)-1-[(1,3-benzodioxol-5-yl)carbonyl]-, hydrochloride; 1353985-61-1; (2-Aminomethyl-piperidin-1-yl)-benzo[1,3]dioxol-5-yl-methanone HCl
EINECS	Contact for details

Quality Control

Our (2-Aminomethyl-Piperidin-1-Yl)-Benzo[1,3]Dioxol-5-Yl-Methanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.