Description

1-(4-Fluoro-Benzyl)-2-(Piperidin-4-Ylmethoxy)-1H-Benzoimidazole Hydrochloride is a high-purity, non-racemic organic compound of significant interest in advanced chemical synthesis. This compound matters as a sophisticated pharmaceutical intermediate or research chemical, offering a precise molecular scaffold for drug discovery and development. It is primarily needed by R&D teams and process chemists in the pharmaceutical, biotechnology, and fine chemical industries working on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or other therapeutic areas.
• Biochemical Research: Used as a reference standard or a probe molecule in pharmacological studies to investigate enzyme inhibition or receptor binding activity.
• Organic Synthesis: Serves as a versatile chiral precursor for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Process Development: Employed in scale-up and optimization studies for the production of active pharmaceutical ingredients (APIs).
• Chemical Library Synthesis: A valuable component for creating diverse screening libraries in early-stage drug discovery programs.

Basic Information

Product Name	1-(4-Fluoro-Benzyl)-2-(Piperidin-4-Ylmethoxy)-1H-Benzoimidazole Hydrochloride
CAS No.	1353966-50-3
Molecular Formula	C20H22FN3O • HCl
Molecular Weight	375.87 g/mol (Free base: 339.41 g/mol)
Synonyms	1-[(4-Fluorophenyl)methyl]-2-[(4-piperidinyl)methoxy]-1H-benzimidazole hydrochloride; 1-(4-Fluorobenzyl)-2-(piperidin-4-ylmethoxy)-1H-benzo[d]imidazole HCl; 2-[(Piperidin-4-yl)methoxy]-1-(4-fluorobenzyl)-1H-benzoimidazole hydrochloride; UNII-8Q9F6289WQ; 8Q9F6289WQ; 1H-Benzimidazole, 1-[(4-fluorophenyl)methyl]-2-[(4-piperidinyl)methoxy]-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-Benzyl)-2-(Piperidin-4-Ylmethoxy)-1H-Benzoimidazole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess, ensuring compliance with research and development standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.