Description

Rafoxanide-13C6 is a stable isotope-labeled analog of the salicylanilide anthelmintic agent, Rafoxanide, where six carbon atoms are replaced with the carbon-13 isotope. This compound is essential as a certified reference material and an internal standard for precise quantitative analysis in advanced mass spectrometry. It is critically needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities engaged in veterinary drug residue analysis, metabolism studies, and method development and validation.

Application

• Internal Standard for LC-MS/MS: Primary use as a quantitative internal standard for the accurate measurement of Rafoxanide in complex biological matrices like meat, milk, and liver tissues.
• Veterinary Drug Residue Testing: Critical for ensuring food safety and compliance with maximum residue limits (MRLs) set by regulatory bodies (e.g., FDA, EMA) in food-producing animals.
• Pharmacokinetic and Metabolism Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in research and development.
• Method Development and Validation: Serves as a key component in developing, optimizing, and validating robust analytical methods according to ICH and other international guidelines.
• Certified Reference Material (CRM): Used for instrument calibration, quality control, and to establish traceability in analytical measurements.
• Doping Control in Animal Sports: Applied in forensic and anti-doping laboratories to detect the misuse of anthelmintic agents in equine and other competitive animals.

Basic Information

Product Name	Rafoxanide-13C6
CAS No.	1353867-98-7
Molecular Formula	C19H1113C6Cl4I2NO2
Molecular Weight	~ 635.9 g/mol (for 13C6 labeled form)
Synonyms	3'-Chloro-4'-(p-chlorophenoxy)-3,5-diiodo[13C6]salicylanilide; 3,5-Diiodo-3'-chloro-4'-(p-chlorophenoxy)[13C6]salicylanilide; [13C6]-Rafoxanide; Rafoxanide (13C6); 13C6-Labeled Rafoxanide; Isotopically Labeled Rafoxanide; Flukanide-13C6 (related trade name analog); Ranide-13C6 (related trade name analog)
EINECS	Contact for details

Quality Control

Every batch of Rafoxanide-13C6 is manufactured and analyzed under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, supported by comprehensive analytical data from techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) are provided with each shipment, detailing batch-specific results for identity, purity (HPLC), isotopic purity, and chemical purity. Our production adheres to cGMP standards suitable for use in regulated laboratory environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. Keep the container tightly sealed to maintain stability and prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to expected mass spectrum
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99 atom % 13C
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.