Description

Triclabendazole-D3 is a deuterium-labeled analog of the anthelmintic drug triclabendazole, specifically designed for use as an internal standard in analytical chemistry. This high-purity stable isotope-labeled compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses. It is primarily used by pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities engaged in drug metabolism, pharmacokinetic studies, and residue testing.

Application

• Internal Standard for LC-MS/MS and GC-MS quantification of triclabendazole and its metabolites.
• Use in pharmacokinetic (PK) and drug metabolism studies for accurate tracer analysis.
• Method development and validation in pharmaceutical quality control laboratories.
• Residue testing in veterinary and food safety analysis.
• Biomedical research investigating the mechanism of action of benzimidazole anthelmintics.
• Calibration standard for high-precision analytical instrumentation.

Basic Information

Product Name	Triclabendazole-D3
CAS No.	1353867-93-2
Molecular Formula	C14H6D3Cl3N2OS
Molecular Weight	362.66 g/mol (approximate)
Synonyms	5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole-d3; 6-Chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)benzimidazole-d3; Deuterated Triclabendazole; Triclabendazole (methyl-d3); [2H3]-Triclabendazole; CGA 89317-d3; Fasinex-d3
EINECS	Contact for details

Quality Control

Our Triclabendazole-D3 is manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical stability. Each batch is characterized by advanced spectroscopic techniques, including NMR and Mass Spectrometry, to confirm deuteration level and structural integrity. We provide comprehensive Certificates of Analysis (COA) detailing purity, isotopic enrichment, and analytical results. Our quality system supports compliance with cGMP and ISO standards for research and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.