Description

Toltrazuril-D3 is a deuterated analog of the established coccidiostat toltrazuril, specifically labeled with three deuterium atoms. This stable isotope-labeled compound is essential for use as an internal standard in advanced analytical methods, ensuring precise quantification and reliable data in complex matrices. It is a critical material for research laboratories, pharmaceutical developers, and contract research organizations (CROs) engaged in veterinary drug residue analysis, pharmacokinetic studies, and metabolic research.

Application

• Internal Standard for LC-MS/MS: Primary application as a quantitative internal standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the analysis of toltrazuril and its metabolites.
• Veterinary Drug Residue Testing: Enables accurate monitoring of drug residues in food-producing animals (poultry, swine) to ensure food safety and regulatory compliance.
• Pharmacokinetic and Metabolism Studies: Used in research to study the absorption, distribution, metabolism, and excretion (ADME) profiles of toltrazuril.
• Method Development and Validation: Critical for developing and validating robust, high-precision analytical methods in quality control and research laboratories.
• Reference Material for Certified Standards: Serves as a key component in the preparation of certified reference materials (CRMs) for calibration.

Basic Information

Product Name	Toltrazuril-D3
CAS No.	1353867-75-0
Molecular Formula	C18H11D3F3N4O4S
Molecular Weight	428.40 g/mol
Synonyms	1-Methyl-3-[3-methyl-4-[4-[(trifluoromethyl)sulfanyl]phenoxy]phenyl]-1,3,5-triazinane-2,4,6-trione-d3; Bay Vi 9142-d3; Toltrazuril (phenyl-d3); Deuterated Toltrazuril; Toltrazuril Internal Standard; Toltrazuril-d3 Isotope; 1,3,5-Triazinane-2,4,6-trione, 1-methyl-3-[3-methyl-4-[4-[(trifluoromethyl)thio]phenoxy]phenyl]-, labeled with deuterium
EINECS	Contact for details

Quality Control

Every batch of Toltrazuril-D3 is manufactured and analyzed under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, supported by comprehensive analytical data including NMR, LC-MS, and HPLC. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic purity (D-enrichment), and confirming the absence of significant unlabeled impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (by NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.