Description

4-Bromo-1-Cyclopropyl-2-Fluorobenzene is a high-value fluorinated and brominated aromatic building block essential for modern synthetic chemistry. Its unique structure, featuring both halogen substituents and a cyclopropyl ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Development: Used in the creation of advanced herbicides, fungicides, and insecticides, where the cyclopropyl and halogen groups contribute to biological activity.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging its rigid aromatic and cyclopropyl components.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine atom.
• Fluorine Chemistry: Utilized in studies exploring the effects of fluorine introduction on the physicochemical properties of organic molecules.
• Chemical Synthesis: Employed as a versatile building block for synthesizing more complex heterocyclic compounds and fine chemicals.

Basic Information

Product Name	4-Bromo-1-Cyclopropyl-2-Fluorobenzene
CAS No.	1353855-10-3
Molecular Formula	C9H8BrF
Molecular Weight	215.06 g/mol
Synonyms	2-Fluoro-4-bromo-1-cyclopropylbenzene; 1-Bromo-4-cyclopropyl-3-fluorobenzene; 4-Bromo-2-fluoro-1-cyclopropylbenzene; Benzene, 4-bromo-1-cyclopropyl-2-fluoro-; 1353855-10-3; 4-Bromo-2-fluorocyclopropylbenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Cyclopropyl-2-Fluorobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, GC, and NMR results, with each shipment. Certificates of Analysis (COA) are available upon request, detailing purity and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.