Description

Methyl 2-(Methyl(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Amino)Acetate is a high-value, functionalized pyridine-boronic ester derivative designed for advanced synthetic chemistry. This compound matters as a versatile and crucial building block in modern pharmaceutical and agrochemical research, enabling the formation of complex molecular architectures via cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used to construct complex pyridine-containing molecules for next-generation herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a functional monomer or linker in the development of organic electronic materials, metal-organic frameworks (MOFs), and advanced polymers.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and probes for studying biological pathways and target engagement.
• Process Chemistry & Scale-Up: Provides a reliable, high-purity starting point for optimizing synthetic routes from laboratory to pilot plant scale.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	Methyl 2-(Methyl(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Amino)Acetate
CAS No.	1353745-96-6
Molecular Formula	C17H27BN2O4
Molecular Weight	334.22 g/mol
Synonyms	Methyl N-methyl-N-[4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]glycinate; 2-[(4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)(methyl)amino]acetic acid methyl ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-[(methoxycarbonylmethyl)methylamino]-4-methylpyridine; Boronic ester pyridine derivative; Pinacol boronate ester intermediate; Suzuki-Miyaura coupling reagent.
EINECS	Contact for details

Quality Control

Our Methyl 2-(Methyl(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Amino)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.