Description

4-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Ylamino)Butan-2-Ol is a high-value, organoboron building block featuring a pyridine core and a pinacol boronate ester group. This compound is essential for modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of active pharmaceutical ingredients (APIs) and advanced organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds between aromatic and heteroaromatic systems.
• Ligand Synthesis: Used in the development of complex ligands for catalysis and material science applications.
• Agrochemical Research: Employed in creating new active ingredients for crop protection products.
• Material Science: A building block for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and probes for biological target identification.

Basic Information

Product Name	4-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Ylamino)Butan-2-Ol
CAS No.	1353718-80-5
Molecular Formula	C16H27BN2O3
Molecular Weight	306.21 g/mol
Synonyms	2-Butanol, 4-[[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methyl-2-pyridinyl]amino]-; 4-((5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methylpyridin-2-yl)amino)butan-2-ol; 4-(4-Methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ylamino)butan-2-ol; Pinacol [4-Methyl-5-[(1-methyl-3-hydroxypropyl)amino]-2-pyridinyl]boronate; 4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(1-methyl-3-hydroxypropyl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our 4-(4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Ylamino)Butan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural integrity suitable for sensitive coupling reactions. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.