Description

3-((4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Oxy)Propan-1-Amine is a high-value, protected boronic ester derivative featuring a primary amine linker, designed for advanced synthetic applications. This compound is critical for enabling efficient, multi-step coupling reactions in controlled environments, offering superior stability and selectivity compared to unprotected boronic acids. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl structures found in drug candidates.
• Proteolysis-Targeting Chimera (PROTAC) Development: Used to synthesize linker components that connect E3 ligase ligands to target protein binders.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides that require specific, complex aromatic architectures.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: The primary amine group facilitates conjugation to peptides, proteins, or fluorescent dyes for diagnostic and biochemical tools.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries in medicinal chemistry campaigns.

Basic Information

Product Name	3-((4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Oxy)Propan-1-Amine
CAS No.	1353718-63-4
Molecular Formula	C15H25BN2O3
Molecular Weight	292.18 g/mol
Synonyms	2-((3-Aminopropoxy)-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-((4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)oxy)propan-1-amine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-[(3-aminopropoxy)-4-methylpyridine; 2-(3-Aminopropoxy)-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(3-aminopropoxy)pyridine; CAS 1353718-63-4
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to strict quality management protocols to support our customers in GMP, ISO, and REACH-compliant manufacturing and research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.