Description

2-Isobutoxy-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, functionalized pyridine derivative containing a pinacol boronate ester group, making it a versatile building block for advanced organic synthesis. Its core value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures in research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-purity intermediates for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex heterocyclic systems.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boron-containing coupling partner for forming carbon-carbon bonds between aromatic and heteroaromatic rings.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate substituted pyridine motifs.
• Materials Science & OLED Development: Employed in the creation of organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers in organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules or for creating chemical probes to study biological pathways.
• Catalyst Ligand Precursor: Acts as a precursor for synthesizing sophisticated ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to custom synthesis organizations for use in client-directed research and scale-up projects.

Basic Information

Product Name	2-Isobutoxy-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1353718-39-4
Molecular Formula	C17H28BNO3
Molecular Weight	305.22 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-isobutoxy-4-methylpyridine; 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-isobutoxypyridine; 4-Methyl-2-isobutoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pyridine, 2-(isobutoxy)-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-Isobutoxy-4-methylpyridine-5-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Isobutoxy-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H and 13C), and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH, TSCA, and other global regulatory frameworks to facilitate seamless integration into international supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.