Description

n-Butyl-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-purity, advanced pharmaceutical intermediate featuring a pinacol boronate ester group, which is critical for modern cross-coupling reactions. This compound is essential for the efficient synthesis of complex molecules, enabling the rapid construction of carbon-carbon bonds under mild conditions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for constructing biaryl and heterobiaryl structures prevalent in drug discovery.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for biochemical and diagnostic applications.
• Process Chemistry & Scale-Up: Provides a reliable and scalable route for the industrial manufacturing of complex organic molecules.

Basic Information

Product Name	n-Butyl-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1353718-21-4
Molecular Formula	C16H27BN2O2
Molecular Weight	290.21 g/mol
Synonyms	2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methyl-4-n-butylpyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methyl-2-(butylamino)pyridine; 2-Pyridinamine, N-butyl-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Boronic acid, B-[2-(butylamino)-3-methyl-5-pyridinyl]-, pinacol ester; 1353718-21-4; Pinacol [2-(butylamino)-3-methyl-5-pyridinyl]boronate
EINECS	Contact for details

Quality Control

Every batch of n-Butyl-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. For long-term storage, consider storing under an inert gas blanket.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.