Description

n-Isopropyl-N,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is primarily needed by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, enabling the introduction of the pyridine-boronate moiety into active structures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: Specifically designed as a coupling partner in palladium-catalyzed Suzuki-Miyaura reactions to form biaryl and heterobiaryl linkages.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological pathways and protein interactions.
• Process Chemistry & Scale-Up: Supports route scouting and optimization for the commercial-scale production of fine chemicals and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	n-Isopropyl-N,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1353718-18-9
Molecular Formula	C16H27BN2O2
Molecular Weight	290.21 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-isopropyl-N,3-dimethylpyridin-2-amine; 2-Pyridinamine, N-(1-methylethyl)-N,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; N-Isopropyl-N,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine; Boronic acid, B-[6-[(1-methylethyl)methylamino]-2-methyl-3-pyridinyl]-, 2,2-dimethyl-1,3-propanediyl ester; Isopropyl-dimethyl-(5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-yl)-amine
EINECS	Contact for details

Quality Control

Our n-Isopropyl-N,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed under an inert atmosphere such as nitrogen or argon to maximize shelf-life stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.