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N1,N1-Dimethyl-N2-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Ethane-1,2-Diamine CAS NO 1353716-15-0


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CAS No.:1353716-15-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N1,N1-Dimethyl-N2-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Ethane-1,2-Diamine is a high-purity, functionalized pyridine-boronic ester derivative designed for advanced synthetic applications. This compound is a critical pharmaceutical intermediate and cross-coupling reagent, enabling the construction of complex molecules through Suzuki-Miyaura reactions. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and materials science who require reliable, high-quality building blocks for drug discovery and fine chemical production.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
  • Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between the boronic ester group and aryl/vinyl halides, crucial for constructing biaryl structures in medicinal chemistry.
  • Ligand Synthesis: Used in the preparation of chelating ligands for catalysis and metal-organic frameworks (MOFs).
  • Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
  • Material Science Precursor: Serves as a monomer or functionalizing agent for advanced polymers and organic electronic materials.
  • Chemical Biology Probe Development: Utilized to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name N1,N1-Dimethyl-N2-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Ethane-1,2-Diamine
CAS No. 1353716-15-0
Molecular Formula C17H30BN3O2
Molecular Weight 319.25 g/mol
Synonyms 2-((5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)amino)-N,N-dimethylethan-1-amine; N,N-Dimethyl-2-((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)amino)ethan-1-amine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-((2-(dimethylamino)ethyl)amino)pyridine; 2-Pyridineethanamine, N,N-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol ester of (6-((2-(dimethylamino)ethyl)amino)pyridin-3-yl)boronic acid
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Quality Control

Our N1,N1-Dimethyl-N2-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl)Ethane-1,2-Diamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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