Description

4-Isopropyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is a high-value, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in the strategic incorporation of a protected boronic ester group, which is essential for modern cross-coupling reactions like the Suzuki-Miyaura reaction. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-aldehyde functionalities.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs or OFETs.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Useful for creating tagged molecules and bioconjugates for research and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in CDMO facilities.

Basic Information

Product Name	4-Isopropyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde
CAS No.	1353580-66-1
Molecular Formula	C16H23BO3
Molecular Weight	274.17 g/mol
Synonyms	2-Formyl-5-isopropylphenylboronic acid pinacol ester; 4-Isopropyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 5-Isopropyl-2-formylphenylboronic acid pinacol ester; (2-Formyl-5-isopropylphenyl)boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-isopropylbenzaldehyde; PINACOL 2-FORMYL-5-ISOPROPYLPHENYLBORONATE
EINECS	Contact for details

Quality Control

Our 4-Isopropyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for pharmaceutical and industrial customers globally.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.