Description

Imidazo(1,2,A)Pyridine-8-Boronic Ester is a high-value, heterocyclic boronic acid derivative used as a key synthetic building block in advanced organic chemistry. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and materials science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, particularly those containing the imidazopyridine scaffold for therapeutic applications.
• Agrochemical Research: Used in the development of new pesticides and herbicides through the construction of complex heterocyclic structures.
• Material Science: Serves as a building block for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Synthesis: Enables Suzuki-Miyaura cross-coupling reactions to form biaryl and other conjugated systems under mild conditions.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: An essential reagent for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Imidazo(1,2,A)Pyridine-8-Boronic Ester
CAS No.	1353387-21-9
Molecular Formula	C9H9BN2O2 (Typical for pinacol ester; contact for specific isomer confirmation)
Molecular Weight	Contact for details
Synonyms	8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-8-boronic acid pinacol ester; 8-Boronic ester of imidazo[1,2-a]pyridine; Imidazopyridine-8-Bpin; CAS 1353387-21-9; 8-(Pinacolboranyl)imidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our Imidazo(1,2,A)Pyridine-8-Boronic Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for sensitive coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and pre-clinical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to prevent hydrolysis and maintain reactivity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical grade)
Water Content (KF)	≤0.5%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.