Description

3'-Fluoro-5'-(Trifluoromethoxy)Acetophenone, 97% is a high-purity fluorinated aromatic ketone building block essential for advanced organic synthesis. This compound matters as a key intermediate for introducing specific fluorine and trifluoromethoxy substituents into target molecules, which are critical for modulating the physicochemical and biological properties of final products. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A versatile building block for the synthesis of novel drug candidates, particularly in CNS and oncology research, where fluorine substitution is crucial for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced lipophilicity and pest system uptake.
• Material Science Research: Serves as a precursor for specialty monomers and polymers, contributing to the creation of advanced materials with unique surface properties and chemical resistance.
• Ligand and Catalyst Development: Employed in the design of complex ligands for catalysis and molecular recognition studies in both academic and industrial settings.
• Fluorine Chemistry Library Building: A critical component for constructing diverse compound libraries aimed at high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	3'-Fluoro-5'-(Trifluoromethoxy)Acetophenone, 97%
CAS No.	1352999-53-1
Molecular Formula	C9H6F4O2
Molecular Weight	222.14 g/mol
Synonyms	1-[3-Fluoro-5-(trifluoromethoxy)phenyl]ethanone; 3-Fluoro-5-(trifluoromethoxy)acetophenone; 3'-Fluoro-5'-(trifluoromethoxy)acetophenone; 1-(3-Fluoro-5-(trifluoromethoxy)phenyl)ethan-1-one; 3-Fluoro-α,α,α-trifluoro-5-methoxyacetophenone; Acetophenone, 3'-fluoro-5'-(trifluoromethoxy)-; Ethanone, 1-[3-fluoro-5-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our 3'-Fluoro-5'-(Trifluoromethoxy)Acetophenone, 97% undergoes rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced chromatographic and spectroscopic techniques to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.