Description

2-Isopropyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value organoboron building block, specifically a pyridine-substituted pinacol boronic ester, essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules with high fidelity and functional group tolerance. This compound is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used to create advanced pyridine-based herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Enables the synthesis of functionalized organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) for electronic and photonic applications.
• Chemical Research & Development: A versatile reagent for academic and industrial research in medicinal chemistry, catalysis, and methodology development.
• Fine Chemical Production: Serves as a precursor for manufacturing complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	2-Isopropyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1352796-58-7
Molecular Formula	C14H22BNO2
Molecular Weight	247.14 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-isopropylpyridine; 2-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Isopropylpyridine-4-boronic acid pinacol ester; 4-(2-Isopropylpyridin-4-yl)boronic acid pinacol ester; 2-Isopropyl-4-pyridinylboronic acid pinacol ester; Pinacol 2-Isopropylpyridine-4-boronate; 2-Isopropyl-4-boronopyridine pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Isopropyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated) or -20°C for extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.