Description

2-[(Prop-2-Yl)Oxy]-1,3-Thiazole-5-Boronic Acid, Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for Suzuki-Miyaura cross-coupling reactions. This compound, with CAS number 1352652-22-2, is critical for the efficient synthesis of complex heterocyclic molecules, offering excellent stability and reactivity. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology, antiviral, and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Synthesis: A versatile reagent for Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds under mild conditions.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis.
• Academic & Contract Research: Essential for methodological development and library synthesis in academic and CRO laboratories.

Basic Information

Product Name	2-[(Prop-2-Yl)Oxy]-1,3-Thiazole-5-Boronic Acid, Pinacol Ester
CAS No.	1352652-22-2
Molecular Formula	C12H20BNO3S
Molecular Weight	269.17 g/mol
Synonyms	2-[(Prop-2-en-1-yl)oxy]-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole; 2-(Allyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(prop-2-en-1-yloxy)-1,3-thiazole; 2-Allyloxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; Thiazole-5-boronic acid, 2-(2-propen-1-yloxy)-, pinacol ester; CAS 1352652-22-2; Allyloxy-thiazole boronic ester
EINECS	Contact for details

Quality Control

Every batch of 2-[(Prop-2-Yl)Oxy]-1,3-Thiazole-5-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.