Description

2-Amino-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is a high-value, multifunctional boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery, catalyst development, and the synthesis of novel organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling.
• Material Science: Serves as a monomer or building block for creating conjugated polymers and organic semiconductors used in OLEDs and electronic devices.
• Chemical Research & Development: A versatile reagent for constructing complex biaryl and heterobiaryl structures in academic and industrial R&D laboratories.
• Ligand and Catalyst Development: Utilized in the preparation of novel bidentate ligands and organometallic catalysts.
• Diagnostic Reagent Synthesis: Employed in the creation of fluorescent probes and molecular imaging agents.

Basic Information

Product Name	2-Amino-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile
CAS No.	1352575-06-4
Molecular Formula	C₁₃H₁₇BN₂O₂
Molecular Weight	244.10 g/mol
Synonyms	2-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 3-Cyano-2-aminophenylboronic acid pinacol ester; 2-Amino-3-(pinacolatoboryl)benzonitrile; 2-Cyano-6-aminophenylboronic acid pinacol ester; (2-Amino-3-cyanophenyl)boronic acid pinacol ester; 1352575-06-4; 2-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; Boronic acid, B-(2-amino-3-cyanophenyl)-, pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Amino-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.