Description

n-Butyl-N,4-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-value boronic ester derivative and a key pharmaceutical intermediate designed for advanced synthesis. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern medicinal chemistry for constructing complex molecules. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aryl or vinyl halides and boronic acids/esters, facilitating the construction of complex biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific pyridine-boronate motifs.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and activity-based protein profiling (ABPP) agents.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	n-Butyl-N,4-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1352414-68-6
Molecular Formula	C17H29BN2O2
Molecular Weight	304.24 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-butyl-4-methylpyridin-2-amine; 2-Amino-N-butyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; N-Butyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine; 1352414-68-6; Boronic acid, B-[2-[(butylamino)-4-methyl-5-pyridinyl]]-, 1,3,2-dioxaborolane ester; Pinacol [2-[(butylamino)-4-methyl-5-pyridinyl]]boronate
EINECS	Contact for details

Quality Control

Every batch of our n-Butyl-N,4-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is produced and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, NMR (1H, 13C, 11B), and mass spectrometry to confirm identity and purity. A detailed Certificate of Analysis (COA) is supplied with each shipment, ensuring traceability and compliance with your internal and regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label/COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.