Description

n-Benzyl-n-Ethyl-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-value, synthetically versatile boronic ester derivative used as a key building block in modern organic synthesis. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the pyridine-boronate moiety is incorporated to enhance biological activity and selectivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring bespoke boronic acid derivatives.
• Academic & Institutional Research: Used in university and institutional laboratories for methodological development in catalysis and new synthetic route exploration.

Basic Information

Product Name	n-Benzyl-n-Ethyl-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1352414-58-4
Molecular Formula	C21H29BN2O2
Molecular Weight	352.28 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-benzyl-N-ethyl-3-methylpyridin-2-amine; 2-Pyridinamine, N-benzyl-N-ethyl-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; N-Benzyl-N-ethyl-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine; 1352414-58-4; BRN 2414-58-4; Boronic ester pyridine derivative; N-Benzyl-N-ethyl-3-methyl-5-(pinacolboron)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our n-Benzyl-n-Ethyl-3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation, as boronic esters can be sensitive to hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (by titration)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.