Description

3-Bromo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is a high-purity, multi-functional organic building block that serves as a critical intermediate in advanced chemical synthesis. Its core value lies in the strategic combination of a reactive aldehyde group and a protected boronic acid pinacol ester, enabling precise cross-coupling and subsequent functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its bifunctional reactivity.
• Ligand and Catalyst Development: Serves as a building block for creating sophisticated ligands and organometallic catalysts used in asymmetric synthesis.
• Organic Electronic Materials: A valuable monomer for constructing π-conjugated systems in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for bioimaging and diagnostic applications.
• Polymer Chemistry: Incorporated as a functional monomer to introduce boronate or aldehyde handles into specialty polymers and dendrimers.

Basic Information

Product Name	3-Bromo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde
CAS No.	1352399-74-6
Molecular Formula	C₁₃H₁₆BBrO₃
Molecular Weight	311.0 g/mol
Synonyms	3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde; 5-Bromo-3-formylphenylboronic acid pinacol ester; (3-Bromo-5-formylphenyl)boronic acid pinacol ester; 3-Bromo-5-(pinacolatoboryl)benzaldehyde; 3-Formyl-5-bromophenylboronic acid pinacol ester; 1352399-74-6; 3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.