Description

2-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Imidazo[1,2-A]Pyridine is a high-value boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, enabling the introduction of the imidazopyridine moiety.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Suzuki-Miyaura Cross-Coupling Reactions: The protected boronic ester group facilitates palladium-catalyzed coupling with aryl or vinyl halides, a cornerstone reaction for C-C bond formation.
• Ligand and Catalyst Development: Utilized in the synthesis of specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of molecular probes for biological target identification.

Basic Information

Item	Detail
Product Name	2-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Imidazo[1,2-A]Pyridine
CAS No.	1352391-12-8
Molecular Formula	C15H21BN2O2
Molecular Weight	272.15 g/mol
Synonyms	2-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-a]pyridine; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylimidazo[1,2-a]pyridine; 2-Methylimidazo[1,2-a]pyridine-6-boronic acid pinacol ester; 2-Methyl-6-(pinacolatoboryl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-6-boronic acid, 2-methyl-, pinacol ester; CAS 1352391-12-8
EINECS	Contact for details

Quality Control

Our 2-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Imidazo[1,2-A]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via NMR and HPLC, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.