Description

2-(Azetidin-1-Yl)-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient cross-coupling reactions, such as Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery and development programs.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aryl/heteroaryl halides and boronic acids/esters, a cornerstone reaction in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as polymers for OLEDs or organic semiconductors.
• Ligand Synthesis: Can be utilized in the development of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-(Azetidin-1-Yl)-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1352135-90-0
Molecular Formula	C15H23BN2O2
Molecular Weight	274.17 g/mol
Synonyms	4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(azetidin-1-yl)pyridine; 2-(Azetidin-1-yl)-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(azetidin-1-yl)-4-picoline; 2-Azetidin-1-yl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 1352135-90-0; Azetidine-pyridine boronic ester; Pinacol boronate pyridine derivative
EINECS	Contact for details

Quality Control

Our 2-(Azetidin-1-Yl)-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including NMR and HPLC. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation upon opening. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.