Description

3-Chloro-2-Formylphenylboronic Acid Pinacol Ester is a versatile and highly functionalized boronic ester building block, essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, while the aldehyde group offers a secondary reactive site for further derivatization. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for constructing biaryl and heterobiaryl scaffolds prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific halogenated aromatic structures.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or inhibitors for proteomics and target identification studies.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis projects requiring multi-functional aromatic compounds.

Basic Information

Product Name	3-Chloro-2-Formylphenylboronic Acid Pinacol Ester
CAS No.	1352129-62-4
Molecular Formula	C₁₃H₁₆BClO₃
Molecular Weight	266.53 g/mol
Synonyms	(3-Chloro-2-formylphenyl)boronic acid pinacol ester; 2-Formyl-3-chlorophenylboronic acid pinacol ester; 3-Chloro-2-formylbenzeneboronic acid pinacol ester; Pinacol (3-chloro-2-formylphenyl)boronate; 3-Chloro-2-carboxaldehydephenylboronic acid pinacol ester; CAS 1352129-62-4; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Formylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.